Search results for "long-acting β2 agonists"

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Use of ICS/LABA (extra-fine and non-extra-fine) in elderly asthmatics.

2016

Age represents an exclusion criterion in randomized clinical trials designed to test the efficacy and safety of inhaled drugs in asthma. As a consequence, data on efficacy and safety of inhaled corticosteroid (ICS) and long-acting β2 agonist (LABA) combinations in elderly asthmatics are scanty. Older age is associated with an increased proportion of comorbid conditions; in addition, all organ functions undergo a process of senescence, thus reducing their ability to metabolize the agents. Overall, these age-associated conditions may variably, and often unpredictably, affect the metabolism and excretion of respiratory drugs. However, pharmacological treatment of asthma does not follow specifi…

Druglong-acting β2 agonistmedicine.medical_specialtyasthma treatmentmedia_common.quotation_subjectPopulationReviewSettore MED/10 - Malattie Dell'Apparato Respiratorio030204 cardiovascular system & hematologylaw.invention03 medical and health sciences0302 clinical medicineRandomized controlled trialPharmacokineticsInhaled corticosteroidlawmedicinePharmacology (medical)General Pharmacology Toxicology and PharmaceuticseducationAdverse effectIntensive care medicineAsthmamedia_commoneducation.field_of_studyChemical Health and SafetyInhalationbusiness.industryaginglung functionGeneral Medicinemedicine.diseasecomorbidity030228 respiratory systemAnesthesiaPharmacodynamicslong-acting β2 agonistsinhaled corticosteroidsbusinessSafety ResearchTherapeutics and clinical risk management
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